I BACKGROUND 1. Introduction 2. Fibromyalgia definition and epidemiology 3. Pathophysiology of fibromyalgia 4. Assessment and diagnosis II COMMON COMORBIDITIES AND FIBROMYALGIA 5. Headache 6. Chronic fatigue syndrome 7. Irritable bowel syndrome 8. Sleep disturbance 9. Depression and anxiety 10. Obesity and metabolic syndrome III TREATMENT 11. Published recommendations 12. Medication treatments 13. Non-medication treatments 14. Nutritional supplements 15. Clinical handouts IV SPECIAL POPULATIONS 16. Fibromyalgia and pregnancy 17. Fibromyalgia in seniors 18. Gender and ethnic issues Index