Teratogenicity Testing: Methods and Protocols

by Barrow, Paul C.
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ISBN: 9781627031301
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Overview

1. The ICH S5(R2) Guideline for the Testing of Medicinal Agents

L. David Wise

2. Non-Clinical Reproductive Toxicity Testing Requirements for Drugs, Pesticides, and Industrial Chemicals in India and China

K.S. Rao and Jing Dong

3. The Developmental Toxicity Testing of Biologics

Keith P Hazelden

4. The OECD Guidelines for the Testing of Chemicals and Pesticides

Jochen Buschmann

5. Teratology Testing Under REACH

Steve Barton

6. The Teratology Testing of Food Additives

Paul Barrow and François Spezia

7. Developmental Toxicity Testing of Vaccines

Paul Barrow and Linda Allais

8. The Tratology Testing of Cosmetics

François Spézia and Paul Barrow

9. Teratology Studies in the Rat

Mariline Leroy and Linda Allais

10. Teratology Studies in the Mouse

Edward Marsden and Mariline Leroy

11. Combined Fertility and Embryotoxicity Study

Lucie Reynaud and Edward Marsden

12.Teratology Studies in the Rabbit

Linda Allais and Lucie Reynaud

13. Teratology Studies in the Minipig

Peter A. McAnulty

14. Embryofetal Development Studies in Nonhuman Primates

Antje Fuchs, Eberhard Buse, Gerhard F. Weinbauer

15. The Enhanced Pre- and Post-natal Development Study for Monoclonal Antibodies

Gerhard F Weinbauer, Joerg Luft, and Antje Fuchs

16. Skeletal Examination by Alizarin Staining

Lucie Reynaud and Audrey Jocteur-Monrozier

17. Skeletal Examination by Double Staining for Ossified Bone and Cartilaginous Tissue

Steffen Schneider

18. Small Animal Imaging and Examination by Micro-CT

Sergio X. Vasquez, Neha Shah, Alan M. Hoberman

19. Fetal Soft Tissue Examination by Serial Sectioning

Karon Critchell Huntingdon

20. Fetal Soft Tissue Examinations by Microdissection

Mariline Leroy and Audrey Jocteur Monrozier

21. Soft Tissue Examination Of The Fetal Rat And Rabbit Head By Magnetic Resonance Imaging

Julian M French and Neil Woodhouse

22. Historical Control Data in Reproductive and Developmental Toxicity Studies

Eve Mylchreest

23. Reporting of Teratology Studies

Paul Barrow and Lucie Reynaud

24. Maternal Toxicity

Bengt R Danielsson

25. Innovations in Testing Strategies in Reproductive Toxicology

Aldert H. Piersma

26. Predictive Models and Computational Toxicology

Thomas Knudsen, Matthew Martin, Kelly Chandler, Nicole Kleinstreuer, Richard Judson, and Nisha Sipes

27. The Embryonic Stem Cell Test

Sjors H.W. Schulpen and Aldert H. Piersma

28. Zebrafish Teratogenicity Testing

Kimberly C. Brannen, Jeffrey H. Charlap, and Elise M. Lewis

29. Frog Embryo Teratogenesis Assay on Xenopus (FETAX) and Predictivity Compared with In-vivo Mammalian Studies

I. Leconte and I. Mouche

30. The Rat Whole Embryo Culture Assay using the Dysmorphology Score System

Cindy Zhang, Julie Panzica-Kelly, Karen Augustine-Rauch

31. Toxicogenomic Approaches in Developmental Toxicology Testing

Joshua F. Robinson- and Aldert H. Piersma

32. Validation of Alternative Tests for Developmental and Reproductive Toxicology Testing - An ILSI Health and Environmental Sciences Institute Perspective

James H. Kim

33. Regulatory Assessment of Reproductive Toxicology Data

Elizabeth Davidson

34. Hazard and Risk Assessment of Teratogenic Chemicals under REACH

Wiebke Prutner

35. Reproductive Toxicity Risk Assessment for Pesticides

Beate Ulbrich

36. The Thalidomide Disaster, Lessons from the Past

James E Ri

  • Format: Hardcover
  • Author: Barrow, Paul C.
  • ISBN: 9781627031301
  • Condition: Used
  • Dimensions: 10.20 x 1.50
  • Number Of Pages: 601
  • Publication Year: 2012

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